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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH6
All Species:
26.06
Human Site:
T906
Identified Species:
40.95
UniProt:
P52701
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52701
NP_000170.1
1360
152786
T906
E
G
R
F
P
D
L
T
V
E
L
N
R
W
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113749
1360
152750
T906
E
G
R
F
P
D
L
T
T
E
L
N
R
W
D
Dog
Lupus familis
XP_531814
1283
145094
R867
D
Q
A
L
A
D
I
R
E
N
E
Q
S
L
L
Cat
Felis silvestris
Mouse
Mus musculus
P54276
1358
151058
T903
K
G
R
F
P
D
L
T
A
E
L
Q
R
W
D
Rat
Rattus norvegicus
XP_002726765
1361
151628
T906
K
G
R
F
P
D
L
T
A
E
L
N
R
W
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419359
1466
164165
S1012
D
G
R
F
P
D
L
S
A
E
L
K
R
W
D
Frog
Xenopus laevis
NP_001089247
1340
149481
S886
H
G
R
F
P
D
L
S
A
E
L
K
R
W
D
Zebra Danio
Brachydanio rerio
NP_878280
1369
153213
S907
D
G
L
F
P
D
L
S
P
E
L
K
R
W
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUM0
1190
133117
E781
A
A
M
D
S
I
G
E
V
E
K
R
L
K
T
Honey Bee
Apis mellifera
XP_392346
1120
127429
V711
A
K
K
V
G
C
I
V
P
K
K
G
V
D
S
Nematode Worm
Caenorhab. elegans
NP_491163
1186
133609
N777
E
E
Y
D
E
A
L
N
R
V
K
E
A
L
N
Sea Urchin
Strong. purpuratus
XP_797647
1335
149141
A878
R
G
K
Y
P
D
Y
A
D
T
L
E
F
F
E
Poplar Tree
Populus trichocarpa
XP_002320307
1288
142120
Y871
V
T
V
G
K
E
A
Y
L
L
E
V
P
E
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04716
1324
146779
S860
G
Q
S
L
P
N
I
S
S
S
I
K
Y
F
K
Baker's Yeast
Sacchar. cerevisiae
Q03834
1242
140062
A833
T
I
E
I
P
I
S
A
T
K
N
V
P
S
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.3
88.1
N.A.
85.8
86.4
N.A.
N.A.
64.2
66.5
60
N.A.
39
41.2
34.4
48.6
Protein Similarity:
100
N.A.
98.6
91.3
N.A.
92.1
92.8
N.A.
N.A.
75.4
79.9
74.9
N.A.
57.6
58
52.7
66.6
P-Site Identity:
100
N.A.
93.3
6.6
N.A.
80
86.6
N.A.
N.A.
73.3
73.3
66.6
N.A.
13.3
0
13.3
26.6
P-Site Similarity:
100
N.A.
93.3
20
N.A.
86.6
93.3
N.A.
N.A.
86.6
80
80
N.A.
13.3
20
20
53.3
Percent
Protein Identity:
36.1
N.A.
N.A.
33.2
29
N.A.
Protein Similarity:
52
N.A.
N.A.
51.4
49.1
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
7
0
7
7
7
14
27
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
14
0
60
0
0
7
0
0
0
0
7
47
% D
% Glu:
20
7
7
0
7
7
0
7
7
54
14
14
0
7
7
% E
% Phe:
0
0
0
47
0
0
0
0
0
0
0
0
7
14
0
% F
% Gly:
7
54
0
7
7
0
7
0
0
0
0
7
0
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
7
0
7
0
14
20
0
0
0
7
0
0
0
0
% I
% Lys:
14
7
14
0
7
0
0
0
0
14
20
27
0
7
7
% K
% Leu:
0
0
7
14
0
0
54
0
7
7
54
0
7
14
7
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
7
0
7
7
20
0
0
14
% N
% Pro:
0
0
0
0
67
0
0
0
14
0
0
0
14
0
0
% P
% Gln:
0
14
0
0
0
0
0
0
0
0
0
14
0
0
0
% Q
% Arg:
7
0
40
0
0
0
0
7
7
0
0
7
47
0
0
% R
% Ser:
0
0
7
0
7
0
7
27
7
7
0
0
7
7
7
% S
% Thr:
7
7
0
0
0
0
0
27
14
7
0
0
0
0
7
% T
% Val:
7
0
7
7
0
0
0
7
14
7
0
14
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
47
0
% W
% Tyr:
0
0
7
7
0
0
7
7
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _